Enables pyrokinin receptor activity. Involved in neuropeptide signaling pathway. Located in plasma membrane. Orthologous to human NMUR1 (neuromedin U receptor 1) and NMUR2 (neuromedin U receptor 2).
FB Description
Pyrokinin 2 receptor 1 (PK2-R1) encodes a G protein-coupled receptor that binds the neuropeptide encoded by Hug with high affinity. After binding, a second messenger cascade is initiated in cells that are target for the product of Hug (mainly neurons of the central nervous system).