Gene

Vha100-4

Species
Drosophila melanogaster
Symbol
Vha100-4
Name
Vacuolar H[+] ATPase 100kD subunit 4
Synonyms
  • CG7678
  • Vacuolar H[+] ATPase subunit 100-4
Biotype
protein coding gene
Automated Description
Predicted to enable ATPase binding activity. Predicted to contribute to proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in proton transmembrane transport and vacuolar acidification. Predicted to be part of vacuolar proton-transporting V-type ATPase, V0 domain. Predicted to be active in plasma membrane. Is expressed in adult head; copper cell primordium; dorsal epidermis primordium; embryonic/larval midgut; and prothoracic gland. Human ortholog(s) of this gene implicated in autosomal recessive cutis laxa type IIA; autosomal recessive osteopetrosis 1; developmental and epileptic encephalopathy 104; renal tubular acidosis; and wrinkly skin syndrome. Orthologous to several human genes including ATP6V0A1 (ATPase H+ transporting V0 subunit a1); ATP6V0A2 (ATPase H+ transporting V0 subunit a2); and ATP6V0A4 (ATPase H+ transporting V0 subunit a4).
FB Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11629
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
18.3870M18.3875M18.3880M18.3885M18.3890M18.3895M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions