Involved in imaginal disc-derived wing vein specification and transcription elongation by RNA polymerase II. Located in nucleus. Part of elongin complex. Colocalizes with euchromatin. Is expressed in several structures, including adult head; anlage in statu nascendi; antennal anlage; central brain anlage; and central brain anlage in statu nascendi. Used to study candidiasis. Orthologous to several human genes including ELOA2 (elongin A2).
FB Description
Elongin A (EloA) encodes a transcription elongation factor that enhances the catalytic rate of RNA Polymerase II by suppressing its transient pausing. It associates with the products of EloB and EloC.