Version: 8.0.0
Date: Tue Jan 28 2025
Ekar
Drosophila melanogasterFB:FBgn0039916
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Ekar

Species
Drosophila melanogaster
Symbol
Ekar
Name
Eye-enriched kainate receptor
Synonyms
  • CG9935
  • CT36399
Biotype
protein coding gene
Automated Description
Predicted to enable kainate selective glutamate receptor activity. Involved in several processes, including glutamatergic synaptic transmission; optomotor response; and regulation of membrane potential in photoreceptor cell. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in adult head; eye; and photoreceptor neurons. Human ortholog(s) of this gene implicated in Huntington's disease; autosomal recessive intellectual developmental disorder 6; childhood absence epilepsy; and chronic obstructive pulmonary disease. Orthologous to several human genes including GRIK1 (glutamate ionotropic receptor kainate type subunit 1); GRIK2 (glutamate ionotropic receptor kainate type subunit 2); and GRIK3 (glutamate ionotropic receptor kainate type subunit 3).
FB Description
Eye-enriched kainate receptor (Ekar) encodes an ionotropic receptor that responds to the neurotransmitter glutamate.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR18966
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
    Disease Qualifier
    Disease
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
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          Models

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            Sequence Feature Viewer

            Genome location
            Assembly version
            R6
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            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            Ekar molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
            Detection methods
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              Genetic Interactions

              Ekar role
              Ekar genetic perturbation
              Interactor gene
              Interactor species
              Interactor role
              Interactor genetic perturbation
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