Gene

Ekar

Species
Drosophila melanogaster
Symbol
Ekar
Name
Eye-enriched kainate receptor
Synonyms
  • CG9935
  • CT36399
Biotype
protein coding gene
Automated Description
Predicted to enable kainate selective glutamate receptor activity. Involved in several processes, including glutamatergic synaptic transmission; optomotor response; and regulation of membrane potential in photoreceptor cell. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in adult head; eye; and photoreceptor neurons. Human ortholog(s) of this gene implicated in Huntington's disease; autosomal recessive intellectual developmental disorder 6; childhood absence epilepsy; and chronic obstructive pulmonary disease. Orthologous to several human genes including GRIK1 (glutamate ionotropic receptor kainate type subunit 1); GRIK2 (glutamate ionotropic receptor kainate type subunit 2); and GRIK3 (glutamate ionotropic receptor kainate type subunit 3).
FB Description
Eye-enriched kainate receptor (Ekar) encodes an ionotropic receptor that responds to the neurotransmitter glutamate.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR18966
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

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Phenotypes

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    Disease Associations

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      Alleles and Variants

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        Transgenic Alleles

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        (carrying the transgene)
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          Models

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            Sequence Feature Viewer

            Genome location
            Assembly version
            R6
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            Sequence Details

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            Expression

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            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            Ekar molecule type
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              Genetic Interactions

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