Gene

Hexo2

Species
Drosophila melanogaster
Symbol
Hexo2
Name
Hexosaminidase 2
Synonyms
  • beta-N-acetyl-D-glucosaminidase
  • beta-N-acetyl-D-hexosaminidase
Biotype
protein coding gene
Automated Description
Enables beta-N-acetylglucosaminidase activity. Involved in sexual reproduction. Located in plasma membrane. Is expressed in several structures, including adult head; adult heart; embryonic/larval garland cell; larval circulatory system; and larval muscle system. Human ortholog(s) of this gene implicated in Sandhoff disease; Tay-Sachs disease; and spinal muscular atrophy. Orthologous to human HEXA (hexosaminidase subunit alpha) and HEXB (hexosaminidase subunit beta).
FB Description
Hexosaminidase 2 (Hexo2) encodes a beta-N-acetylglucosaminidase involved in carbohydrate metabolism.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR22600
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
8.7100M8.7105M8.7110M8.7115M8.7120M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions