Gene

Hex-t2

Species
Drosophila melanogaster
Symbol
Hex-t2
Name
Hexokinase testis 2
Synonyms
  • anon-WO0140519.203
  • CG32849
Biotype
protein coding gene
Automated Description
Predicted to enable fructokinase activity and glucokinase activity. Predicted to be involved in glucose 6-phosphate metabolic process; hexose metabolic process; and intracellular glucose homeostasis. Predicted to be active in cytosol and mitochondrion. Is expressed in adult head and spermatozoon. Human ortholog(s) of this gene implicated in several diseases, including Charcot-Marie-Tooth disease type 4G; anemia (multiple); artery disease (multiple); glucose metabolism disease (multiple); and hematologic cancer (multiple). Orthologous to several human genes including GCK (glucokinase); HK2 (hexokinase 2); and HK3 (hexokinase 3).
FB Description
Hexokinase testis 2 (Hex-t2) is predicted to encode a testis-specific enzyme involved in hexose metabolism that catalyzes the phosphorylation of hexose to hexose 6-phosphate. It may mediate the initial step of glycolysis by catalyzing the phosphorylation of D-glucose to D-glucose 6-phosphate.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR19443
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
26.4508M26.4510M26.4512M26.4514M26.4516M26.4518M26.4520M26.4522M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions