Gene

PGRP-SB2

Species
Drosophila melanogaster
Symbol
PGRP-SB2
Name
Peptidoglycan recognition protein SB2
Synonyms
  • CG9697
  • PGRP-SB
Biotype
protein coding gene
Automated Description
Predicted to enable N-acetylmuramoyl-L-alanine amidase activity. Predicted to be involved in peptidoglycan catabolic process. Located in extracellular region.
FB Description
Peptidoglycan recognition protein SB2 (PGRP-SB2) encodes a secreted peptidoglycan recognition protein (PGRP) with amidase activity against DAP-type peptidoglycan, a cell wall component found on Gram-negative bacteria and certain Gram positive bacteria. It is strongly induced upon bacterial infection by the immune deficiency pathway, suggesting a role as an immune effector.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11022
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
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16.7266M16.7267M16.7268M16.7269M16.7270M16.7271M16.7272M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions