Gene

fdl

Species
Drosophila melanogaster
Symbol
fdl
Name
fused lobes
Synonyms
  • beta-N-acetyl-D-glucosaminidase
  • beta-N-acetylglucosaminidase
Biotype
protein coding gene
Automated Description
Enables beta-N-acetylglucosaminidase activity. Involved in N-glycan processing; brain development; and rhodopsin biosynthetic process. Located in late endosome and plasma membrane. Colocalizes with Golgi apparatus and endoplasmic reticulum. Is expressed in adult head. Human ortholog(s) of this gene implicated in Sandhoff disease; Tay-Sachs disease; and spinal muscular atrophy. Orthologous to human HEXA (hexosaminidase subunit alpha) and HEXB (hexosaminidase subunit beta).
FB Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR22600
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
12.488M12.490M12.492M12.494M12.496M12.498M12.500M12.502M12.504M12.506M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions