Gene

sens-2

Species
Drosophila melanogaster
Symbol
sens-2
Name
senseless-2
Synonyms
  • CG11243
  • CG17373
Biotype
protein coding gene
Automated Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in embryonic midgut chamber; embryonic/larval midgut; and posterior midgut primordium. Human ortholog(s) of this gene implicated in acute myeloid leukemia; gray platelet syndrome; myelodysplastic syndrome; platelet-type bleeding disorder 17; and severe congenital neutropenia 2. Orthologous to several human genes including GFI1B (growth factor independent 1B transcriptional repressor).
FB Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24381
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
6.822M6.824M6.826M6.828M6.830M6.832M6.834M6.836M6.838M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions