Enables copper ion transmembrane transporter activity. Involved in copper ion transport; intracellular copper ion homeostasis; and response to metal ion. Predicted to be located in membrane. Is expressed in adult heart; embryonic hindgut; embryonic midgut chamber; embryonic/larval midgut; and yolk nucleus. Used to study Wilson disease.
FB Description
Copper transporter 1B (Ctr1B) encodes a protein that ensures copper uptake in the intestine. Ctr1B transcription is upregulated under conditions of copper depletion via the metal-responsive transcription factor encoded by MTF-1.