Gene

Snoo

Species
Drosophila melanogaster
Symbol
Snoo
Name
Sno oncogene
Synonyms
  • CG34421
  • CG7093
Biotype
protein coding gene
Automated Description
Enables co-SMAD binding activity. Involved in dendrite morphogenesis; regulation of SMAD protein signal transduction; and regulation of transmembrane receptor protein serine/threonine kinase signaling pathway. Located in cytosol and nucleus. Is expressed in several structures, including Bolwig organ; egg chamber; ganglia; and germarium. Orthologous to human SKIL (SKI like proto-oncogene) and SKI (SKI proto-oncogene).
FB Description
Sno oncogene (Snoo) encodes a protein that belongs to the highly conserved Sno/Ski family of Smad binding proteins. It specifically binds the product of Med and switches its affinity from the products of Mad to Smox, resulting in antagonism of the product of dpp and facilitation of Activin signaling. Snoo overexpression antagonizes both pathways.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10005
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
7.90M7.91M7.92M7.93M7.94M7.95M7.96M7.97M7.98M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions