Gene

Zdhhc8

Species
Drosophila melanogaster
Symbol
Zdhhc8
Name
Zinc finger DHHC-type containing 8
Synonyms
  • anon-Pen16
  • CG12136
Biotype
protein coding gene
Automated Description
Predicted to enable protein-cysteine S-palmitoyltransferase activity. Is expressed in adult head and larval central nervous system. Orthologous to human ZDHHC5 (zinc finger DHHC-type palmitoyltransferase 5) and ZDHHC8 (zinc finger DHHC-type palmitoyltransferase 8).
FB Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12349
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensZDHHC85 of 9YesYes   
Homo sapiensZDHHC55 of 9YesYes   
Mus musculusZdhhc55 of 9YesYes   
Mus musculusZdhhc85 of 9YesYes   
Rattus norvegicusZdhhc55 of 9YesYes   
Rattus norvegicusZdhhc85 of 9YesYes   
Xenopus tropicaliszdhhc85 of 9YesYes   
Danio reriozdhhc5b7 of 10YesYes  
Danio reriozdhhc8b6 of 10NoYes  
Danio reriozdhhc5a6 of 10NoYes  
Caenorhabditis elegansdhhc-84 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
app178241283 of 8  

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
Phenotype Term
Annotation details
References
abnormal body size | larval stage
abnormal developmental rate | larval stage
fertile
lethal - all die before end of larval stage
majority die during second instar larval stage
viable
visible | larval stage
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Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
No data available

Alleles and Variants

Genome location
Assembly version
R6
Viewer Help
9.325M9.330M9.335M9.340M9.345M9.350M9.355M
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
Zdhhc8KO1
  • dZDHHC8[KO1]
  • dZDHHC8KO1
allele
Yes
Zdhhc8KO2
  • dZDHHC8[KO2]
  • dZDHHC8KO2
allele
Yes
Zdhhc8G0250
  • CG34449[G0250]
  • CG34449G0250
allele
Zdhhc8e03903
  • CG34449[e03903]
  • CG34449e03903
allele
Zdhhc8EY00880
  • CG34449[EY00880]
  • CG34449EY00880
allele with one associated variant
insertion
  • 5 prime UTR variant
Zdhhc8f05814
  • CG34449[f05814]
  • CG34449f05814
allele with one associated variant
insertion
  • intron variant
Zdhhc8f05850
  • CG32705[f05850]
  • CG32705f05850
allele with one associated variant
insertion
  • intron variant
Zdhhc8c05709
  • CG34449[c05709]
  • CG34449c05709
allele with one associated variant
insertion
  • intron variant
Zdhhc8MI01245
  • CG34449[MI01245]
  • CG34449MI01245
allele with one associated variant
insertion
  • intron variant
Zdhhc8MI01245-TG4.2
  • CG34449[MI01245-TG4.2]
  • CG34449MI01245-TG4.2
allele with one associated variant
insertion
  • intron variant
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Transgenic Alleles

Species
(carrying the transgene)
Allele symbol
Transgenic construct
Expressed components
Knock-down targets
Regulatory regions
Has Disease Annotations
Has Phenotype Annotations
Drosophila melanogasterBCL7-likeSAM.dCas9.GS03942
  • Tag:MS2
Drosophila melanogasterZdhhc8GD3294
  • UASt
Drosophila melanogasterZdhhc8GD3540
  • UASt
Drosophila melanogasterZdhhc8GD5212
  • UASt
Drosophila melanogasterZdhhc8HMJ22999
  • UAS
Drosophila melanogasterZdhhc8RNAi.UAS.3
  • UAS
Drosophila melanogasterZdhhc8SAM.dCas9.GS03942
  • Tag:MS2
Drosophila melanogasterZdhhc8TKO.GS04177
Drosophila melanogasterZdhhc8UAS.Tag:Myc
  • UASt
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Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
9.325M9.330M9.335M9.340M9.345M9.350M9.355MZdhhc8-RA (Zdhhc8)Zdhhc8-RB (Zdhhc8)Zdhhc8-RC (Zdhhc8)Zdhhc8-RD (Zdhhc8)Zdhhc8-RE (Zdhhc8)Zdhhc8-RF (Zdhhc8)Zdhhc8-RG (Zdhhc8)CG34450-RA (CG34450)

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
all annotationsall anatomical structuresalimentary part of gastrointestinal systemchemosensory systemcirculatory systemendocrine systemexocrine systemhemolymphoid systemhepatobiliary systemintegumental systemmechanosensory systemmusculoskeletal systemnervous systemrenal systemreproductive systemrespiratory systemsensory systemvestibulo-auditory systemvisual systemendodermectodermmesodermmesenchymeadipose tissueappendageentire extraembryonic componentimaginal precursorpharyngeal archotherall stagesembryo stagepost embryonic, pre-adultpost-juvenile adult stageall cellular componentsextracellular regionplasma membranesynapsecell junctioncell projectioncytoplasmic vesicleendosomevacuolegolgi apparatusendoplasmic reticulumcytosolmitochondrionnucleuschromosomecytoskeletonprotein-containing complexother locations
Zdhhc8 (Dme)
Zdhhc5 (Mmu)
Zdhhc8 (Mmu)
Zdhhc5 (Rno)
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

18 interactor genes based on 18 annotations
Zdhhc8 molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
asprDrosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
CG10650Drosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
CG17666Drosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
CG34168Drosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
Fur2Drosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
haleDrosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
Hsp23Drosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
LanB1Drosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
Mst84DaDrosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
Mst84DbDrosophila melanogaster
protein
  • two hybrid
PMID:14605208
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Genetic Interactions

Zdhhc8 role
Zdhhc8 genetic perturbation
Interactor gene
Interactor species
Interactor role
Interactor genetic perturbation
Interaction type
Phenotype or trait
Source
Reference
enhanced gene
Ras64BDrosophila melanogaster
enhancer gene
genetic enhancement
    PMID:30735487
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