Gene

gish

Species
Drosophila melanogaster
Symbol
gish
Name
gilgamesh
Synonyms
  • anon-WO0118547.425
  • casein kinase 1gamma
Biotype
protein coding gene
Automated Description
Enables protein serine/threonine kinase activity. Involved in several processes, including olfactory learning; positive regulation of signal transduction; and sperm individualization. Located in cytoplasmic side of plasma membrane; nucleus; and sperm individualization complex. Is expressed in several structures, including adult brain; adult central complex; adult head; synaptic neuropil domain; and synaptic neuropil subdomain. Orthologous to several human genes including CSNK1G2 (casein kinase 1 gamma 2).
FB Description
gilgamesh (gish) encodes a plasma membrane-associated kinase that regulates Hedgehog and Wingless signaling activity. It is involved in planar cell polarity via regulation of Rab11-mediated vesicle trafficking
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11909
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

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    Disease Associations

    Cases where the expected disease association was NOT found
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    Alleles and Variants

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      Transgenic Alleles

      Species
      (carrying the transgene)
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        Models

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          Sequence Feature Viewer

          Genome location
          Assembly version
          R6
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          Sequence Details

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          Expression

          Primary Sources
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          gish molecule type
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            Genetic Interactions

            gish role
            gish genetic perturbation
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