Enables guanyl-nucleotide exchange factor activity. Involved in several processes, including Ras protein signal transduction; positive regulation of smoothened signaling pathway; and sarcomere organization. Predicted to be active in plasma membrane. Is expressed in several structures, including adult head; gut section; larval central nervous system; somatic trunk mesoderm; and visceral trunk mesoderm. Orthologous to human RAPGEF1 (Rap guanine nucleotide exchange factor 1).
FB Description
C3G guanyl-nucleotide exchange factor (C3G) is expressed in the developing embryonic muscles and its product plays a role in body wall muscle development during larval stages.