Enables integrin binding activity. Involved in several processes, including apposition of dorsal and ventral imaginal disc-derived wing surfaces; border follicle cell migration; and germ-band shortening. Located in focal adhesion. Is expressed in several structures, including adult head; adult heart; amnioserosa; embryonic/larval midgut primordium; and muscle attachment site. Orthologous to several human genes including TLN2 (talin 2).
FB Description
rhea (rhea) encodes fly talin, a large adaptor protein that is essential for all adhesive functions of integrins. It also has at least one role independent of integrins: repressing shg transcription in follicle cells.