Gene

2mit

Species
Drosophila melanogaster
Symbol
2mit
Name
2mit
Synonyms
  • CG10148
  • CG17319
Biotype
protein coding gene
Automated Description
Involved in short-term memory. Is expressed in several structures, including Kenyon cell; adult gnathal ganglion; adult head; ellipsoid body; and presumptive embryonic/larval nervous system.
FB Description
2mit (2mit) encodes a putative leucine-rich repeat transmembrane protein that is mainly expressed in the developing central nervous system. In the adult, it has a role in short-term memory.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45617
Stringency:
Additional filters to further constrain the results:
No ortholog matching your filter. Please try a less stringent filter.
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
CG78961128236212 of 8  
CG423462118537213 of 8  
Toll-73130031202 of 8  
atk5111035212 of 8  
ltl694635212 of 8  
caps788934213 of 8  
conv888136212 of 8  
CG4168964339233 of 8  
chp1068438212 of 8  
Tollo1166035243 of 8  
Gp1501261136242 of 8  
cDIP1355039233 of 8  
CG67491445739283 of 8  
trn1547640242 of 8  
CG49501641341243 of 8  
CG147621737546302 of 8  
CG78001842340242 of 8  
alrm1941239262 of 8  
CG58102039241232 of 8  

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
Phenotype Term
Annotation details
References
abnormal medium-term memory | adult stage
abnormal memory
fertile
viable
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Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

Genome location
Assembly version
R6
Viewer Help
13.125M13.130M13.135M13.140M13.145M13.150M13.155M
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
2mitMI01601
  • 2mit[MI01601]
allele with one associated variant
insertion
  • intron variant
2mitMI09935
  • 2mit[MI09935]
allele with one associated variant
insertion
  • intron variant
2mitMI05471
  • 2mit[MI05471]
allele with one associated variant
insertion
  • intron variant
2mitc03963
  • 2mit[c03963]
allele with one associated variant
insertion
  • intron variant
Yes
NT_033777.3:g.13125877C>Avariant
SNP
  • intron variant
NT_033777.3:g.13127095C>Tvariant
SNP
  • intron variant
NT_033777.3:g.13127237T>Cvariant
SNP
  • intron variant
NT_033777.3:g.13153869T>Avariant
SNP
  • intron variant
NT_033777.3:g.13139637A>Cvariant
SNP
  • intron variant
NT_033777.3:g.13139937G>Avariant
SNP
  • intron variant
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Transgenic Alleles

Species
(carrying the transgene)
Allele symbol
Transgenic construct
Expressed components
Knock-down targets
Regulatory regions
Has Disease Annotations
Has Phenotype Annotations
Drosophila melanogaster2mitGD14446
  • UASt
Drosophila melanogaster2mitGD22
  • UASt
Drosophila melanogaster2mitGD2518
  • UASt
Drosophila melanogaster2mitGD519
  • UASt
Drosophila melanogaster2mitHM05039
  • UAS
Drosophila melanogaster2mitHMJ23847
  • UAS
Drosophila melanogaster2mitKK104964
  • UASt
Drosophila melanogaster2mitNIG.10148R
  • UASt
Drosophila melanogaster2mitRNAi.UAS.cBa
  • UAS
Drosophila melanogaster2mitUAS.Tag:HA
  • UASt
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Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
13.125M13.130M13.135M13.140M13.145M13.150M13.155M2mit-RA (2mit)2mit-RB (2mit)2mit-RC (2mit)2mit-RD (2mit)lncRNA:CR45109-RA (lncRNA:CR45109)CG34308-RC (CG34308)lncRNA:CR46019-RA (lncRNA:CR46019)timeout-RA (timeout)

Sequence Details

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Expression

Primary Sources
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

6 interactor genes based on 7 annotations
2mit molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
apolppDrosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
Argk1Drosophila melanogaster
protein
  • two hybrid
PMID:33011181
protein
Argk1Drosophila melanogaster
protein
  • anti tag coimmunoprecipitation
PMID:33011181
protein
armDrosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
PcdDrosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
TctpDrosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
wdnDrosophila melanogaster
protein
  • two hybrid
PMID:14605208
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Genetic Interactions

No data available