Gene

wol

Species
Drosophila melanogaster
Symbol
wol
Name
wollknaeuel
Synonyms
  • ALG5
  • alg5
Biotype
protein coding gene
Automated Description
Enables dolichyl-phosphate beta-glucosyltransferase activity. Involved in several processes, including gastrulation; protein glycosylation; and septate junction assembly. Located in endoplasmic reticulum. Is expressed in several structures, including adult head; embryonic proventriculus inner layer; gland; gut section; and imaginal disc. Human ortholog(s) of this gene implicated in polycystic kidney disease 7. Orthologous to human ALG5 (ALG5 dolichyl-phosphate beta-glucosyltransferase).
FB Description
wollknaeuel (wol) encodes a protein belonging to the the glycosyltransferase 2 family. It contributes to N-glycan biosynthesis and is involved in epidermal differentiation including maintenance of cell polarity and cuticle formation.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10859
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
8.3014M8.3016M8.3018M8.3020M8.3022M8.3024M8.3026M8.3028M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions