Enables dolichyl-phosphate beta-glucosyltransferase activity. Involved in several processes, including gastrulation; protein glycosylation; and septate junction assembly. Located in endoplasmic reticulum. Is expressed in several structures, including adult head; embryonic proventriculus inner layer; gland; gut section; and imaginal disc. Human ortholog(s) of this gene implicated in polycystic kidney disease 7. Orthologous to human ALG5 (ALG5 dolichyl-phosphate beta-glucosyltransferase).
FB Description
wollknaeuel (wol) encodes a protein belonging to the the glycosyltransferase 2 family. It contributes to N-glycan biosynthesis and is involved in epidermal differentiation including maintenance of cell polarity and cuticle formation.