Gene

Xrp1

Species
Drosophila melanogaster
Symbol
Xrp1
Name
Xrp1
Synonyms
  • 2515
  • anon-EST:Liang-2.44
Biotype
protein coding gene
Automated Description
Enables P-element binding activity and chromatin binding activity. Involved in chromosome organization and double-strand break repair. Located in nucleus. Part of DNA repair complex. Is expressed in several structures, including anal pad primordium; dorsal epidermis primordium; embryonic anal pad; embryonic dorsal epidermis; and embryonic head epidermis.
FB Description
Xrp1 (Xrp1) encodes an AT-Hook, bZip DNA binding protein involved in genome stability maintenance. It heterodimerizes with the product of Irbp18 to bind to P element sequences contributing to transposition. It is induced by p53 following X-irradiation and by mutations or knockdown of caz or ribosomal protein (Rp) encoding genes. It contributes to the slow growth of Minute (Rp+/-) mutants cell-autonomously by inhibiting translation and non-autonomously through regulation of the product of Ilp8.
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
18.916M18.918M18.920M18.922M18.924M18.926M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions