Enables P-element binding activity and chromatin binding activity. Involved in chromosome organization and double-strand break repair. Located in nucleus. Part of DNA repair complex. Is expressed in several structures, including anal pad primordium; dorsal epidermis primordium; embryonic anal pad; embryonic dorsal epidermis; and embryonic head epidermis.
FB Description
Xrp1 (Xrp1) encodes an AT-Hook, bZip DNA binding protein involved in genome stability maintenance. It heterodimerizes with the product of Irbp18 to bind to P element sequences contributing to transposition. It is induced by p53 following X-irradiation and by mutations or knockdown of caz or ribosomal protein (Rp) encoding genes. It contributes to the slow growth of Minute (Rp+/-) mutants cell-autonomously by inhibiting translation and non-autonomously through regulation of the product of Ilp8.