Gene

sxc

Species
Drosophila melanogaster
Symbol
sxc
Name
super sex combs
Synonyms
  • BcDNA:GH04245
  • CG10392
Biotype
protein coding gene
Automated Description
Enables protein O-acetylglucosaminyltransferase activity. Involved in several processes, including locomotor rhythm; positive regulation of fibroblast growth factor receptor signaling pathway; and protein O-linked glycosylation. Is expressed in adult head and organism. Used to study non-syndromic X-linked intellectual disability 106. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 106. Orthologous to human OGT (O-linked N-acetylglucosamine (GlcNAc) transferase).
FB Description
super sex combs (sxc) is a polycomb group gene that encodes a O-GlcNAc transferase involved in epigenetic gene silencing.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR44366
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
5.308M5.310M5.312M5.314M5.316M5.318M5.320M5.322M5.324M5.326M5.328M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions