Gene

capt

Species
Drosophila melanogaster
Symbol
capt
Name
capulet
Synonyms
  • Acap
  • Act up
Biotype
protein coding gene
Automated Description
Predicted to enable actin binding activity and adenylate cyclase binding activity. Involved in several processes, including cytoskeleton organization; muscle cell cellular homeostasis; and neuron development. Located in cytoplasm. Is expressed in several structures, including adult head; adult heart; amnioproctodeal invagination; epithelial furrow; and ganglia. Human ortholog(s) of this gene implicated in dilated cardiomyopathy. Orthologous to human CAP1 (cyclase associated actin cytoskeleton regulatory protein 1) and CAP2 (cyclase associated actin cytoskeleton regulatory protein 2).
FB Description
capulet (capt) encodes a conserved actin binding protein that functions across eukaryotes to negatively regulate actin filament assembly. Different types of actin filament formation are differentially affected by the loss of capt.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10652
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
1.152M1.153M1.154M1.155M1.156M1.157M1.158M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions