Gene

ps

Species
Drosophila melanogaster
Symbol
ps
Name
pasilla
Synonyms
  • BcDNA:RE47781
  • CG16765
Biotype
protein coding gene
Automated Description
Enables pre-mRNA intronic binding activity. Involved in positive regulation of RNA splicing and regulation of alternative mRNA splicing, via spliceosome. Located in nucleus. Is expressed in several structures, including Malpighian tubule primordium; embryonic/larval midgut primordium; epithelium; gut section; and somatic trunk mesoderm derivative. Orthologous to human NOVA1 (NOVA alternative splicing regulator 1) and NOVA2 (NOVA alternative splicing regulator 2).
FB Description
pasilla (ps) encodes a nuclear RNA binding protein implicated in splicing. It is expressed at high levels in the embryonic salivary gland and other tissues. Loss of function results in a significant reduction in secretory volume and secretory vesicles in the salivary gland and irregular gland morphology.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10288
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
9.420M9.425M9.430M9.435M9.440M9.445M9.450M9.455M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions