Gene

tobi

Species
Drosophila melanogaster
Symbol
tobi
Name
target of brain insulin
Synonyms
  • alpha-Glucosidase
  • CG11909
Biotype
protein coding gene
Automated Description
Predicted to enable hydrolase activity, hydrolyzing O-glycosyl compounds. Predicted to be involved in carbohydrate metabolic process. Is expressed in adult gut; adult head; and fat cell. Human ortholog(s) of this gene implicated in basal ganglia calcification. Orthologous to human MYORG (myogenesis regulating glycosidase).
FB Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR43053
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensMYORG7 of 9YesYes   
Mus musculusMyorg8 of 9YesYes   
Rattus norvegicusMyorg7 of 9YesYes   
Xenopus tropicalismyorg7 of 9YesYes   
Danio reriomyorg7 of 10YesYes  
Danio reriosi:ch211-117c19.17 of 10YesYes  
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
CG33080171444264 of 8  
GCS2α281334203 of 8  

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

No mapped variant information available
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
NT_033777.3:g.25346522C>Tvariant
SNP
  • 5 prime UTR variant
NT_033777.3:g.25345474T>Cvariant
SNP
  • 5 prime UTR variant
NT_033777.3:g.25345843C>Tvariant
SNP
  • 5 prime UTR variant
NT_033777.3:g.25346896T>Cvariant
SNP
  • 5 prime UTR variant
NT_033777.3:g.25344764A>Tvariant
SNP
  • 3 prime UTR variant
NT_033777.3:g.25346687C>Tvariant
SNP
  • 5 prime UTR variant
NT_033777.3:g.25346893G>Avariant
SNP
  • 5 prime UTR variant
NT_033777.3:g.25344898A>Gvariant
SNP
  • missense variant
NT_033777.3:g.25345198C>Tvariant
SNP
  • 5 prime UTR variant
NT_033777.3:g.25346572T>Avariant
SNP
  • 5 prime UTR variant
Showing 1 - 10 of 51 rows
per page

Transgenic Alleles

Species
(carrying the transgene)
Allele symbol
Transgenic construct
Expressed components
Knock-down targets
Regulatory regions
Has Disease Annotations
Has Phenotype Annotations
Drosophila melanogastertobi1B5.Sym.UAS
  • UAS
Drosophila melanogastertobi1B5.Sym.UAS
  • UAS
Drosophila melanogastertobiGD6263
  • UASt
Drosophila melanogastertobiHMJ02101
  • UAS
Drosophila melanogastertobiKK100897
  • UASt
Drosophila melanogastertobiNIG.11909R
  • UASt
Drosophila melanogastertobiRNAi.2A2.UAS
  • UAS
Drosophila melanogastertobiUAS.cBa
  • UASt
Drosophila melanogastertobia.1B5.Sym.UAS
  • UAS
Drosophila melanogastertobia.1B5.Sym.UAS
  • UAS
Showing 1 - 10 of 10 rows
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Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
25.3448M25.3450M25.3452M25.3454M25.3456M25.3458M25.3460M25.3462M25.3464M25.3466M25.3468M

Sequence Details

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Expression

Primary Sources
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

9 interactor genes based on 9 annotations
tobi molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
CalrDrosophila melanogaster
protein
  • experimental knowledge based
PMID:22036573
protein
CG4325Drosophila melanogaster
protein
  • experimental knowledge based
PMID:22036573
protein
cluDrosophila melanogaster
protein
  • experimental knowledge based
PMID:22036573
protein
ERp60Drosophila melanogaster
protein
  • experimental knowledge based
PMID:22036573
protein
I-2Drosophila melanogaster
protein
  • experimental knowledge based
PMID:22036573
protein
PcdDrosophila melanogaster
protein
  • experimental knowledge based
PMID:22036573
protein
STUB1Drosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
tsrDrosophila melanogaster
protein
  • experimental knowledge based
PMID:22036573
protein
ttm50Drosophila melanogaster
protein
  • two hybrid
PMID:14605208
Showing 1 - 9 of 9 rows
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Genetic Interactions

No data available