Gene

larp

Species
Drosophila melanogaster
Symbol
larp
Name
La related protein
Synonyms
  • 0031/08
  • 0225/29
Biotype
protein coding gene
Automated Description
Enables mRNA 5'-UTR binding activity and poly-pyrimidine tract binding activity. Involved in several processes, including mitochondrion inheritance; positive regulation of mitochondrial DNA replication; and regulation of cytoplasmic translation. Located in cytosol. Is extrinsic component of mitochondrial outer membrane. Colocalizes with mitochondrion. Is expressed in several structures, including adult brain; embryonic/larval midgut primordium; germ layer; germline cell; and synaptic neuropil domain. Orthologous to several human genes including LARP1 (La ribonucleoprotein 1, translational regulator).
FB Description
La related protein (larp) encodes a protein that associates and interacts with poly(A)-binding protein. It is required for multiple processes in male meiosis and syncytial embryo development.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR22792
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
28.320M28.322M28.324M28.326M28.328M28.330M28.332M28.334M28.336M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions