Gene

SmE

Species
Drosophila melanogaster
Symbol
SmE
Name
Small ribonucleoprotein particle protein SmE
Synonyms
  • BcDNA:GM19936
  • CG18591
Biotype
protein coding gene
Automated Description
Predicted to enable RNA binding activity. Predicted to be involved in spliceosomal snRNP assembly. Located in nucleus. Part of small nuclear ribonucleoprotein complex. Is expressed in adult head and adult heart. Human ortholog(s) of this gene implicated in hepatocellular carcinoma; hypotrichosis 1; hypotrichosis 11; and lupus nephritis. Orthologous to human SNRPE (small nuclear ribonucleoprotein polypeptide E).
FB Description
Small ribonucleoprotein particle protein SmE (SmE) encodes an RNA binding protein that functions as part of a heteroheptameric ring structure called the Sm core. This complex binds to spliceosomal small nuclear RNAs (e.g. U1, U2, U4 and U5) and helps to carry out pre-mRNA splicing. It also forms a heterotrimeric sub-complex with the products of SmF and SNRPG.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11193
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
7.88495M7.88500M7.88505M7.88510M7.88515M7.88520M7.88525M7.88530M7.88535M7.88540M7.88545M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions