Version: 8.0.0
Date: Tue Jan 28 2025
snRNP-U1-C
Drosophila melanogasterFB:FBgn0261792
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

snRNP-U1-C

Species
Drosophila melanogaster
Symbol
snRNP-U1-C
Name
small ribonucleoprotein particle U1 subunit C
Synonyms
  • BcDNA:RH29440
  • C
Biotype
protein coding gene
Automated Description
Predicted to enable pre-mRNA 5'-splice site binding activity. Involved in regulation of alternative mRNA splicing, via spliceosome. Located in nucleus. Part of small nuclear ribonucleoprotein complex. Is expressed in several structures, including anterior endoderm; anterior endoderm anlage; central brain primordium; embryonic/larval midgut primordium; and ganglia. Human ortholog(s) of this gene implicated in connective tissue disease; mixed connective tissue disease; and systemic lupus erythematosus. Orthologous to human SNRPC (small nuclear ribonucleoprotein polypeptide C).
FB Description
small ribonucleoprotein particle U1 subunit C (snRNP-U1-C) encodes a U1 snRNA-containing protein that initiates spliceosome assembly by binding to the 5' splice site in pre-mRNA.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR31148
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
      Has Disease Annotations
      Has Phenotype Annotations
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        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
        Modifier
        Source
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          Sequence Feature Viewer

          Genome location
          Assembly version
          R6
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          Data currently unavailable; sequence viewer under construction

          Sequence Details

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          Expression

          Primary Sources
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          snRNP-U1-C molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
          Reference
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            Genetic Interactions

            snRNP-U1-C role
            snRNP-U1-C genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
            Reference
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