Enables non-membrane spanning protein tyrosine kinase activity. Involved in several processes, including adherens junction maintenance; negative regulation of imaginal disc growth; and positive regulation of hippo signaling. Predicted to be located in cell-cell junction. Predicted to be active in plasma membrane. Is expressed in salivary gland. Orthologous to several human genes including CSK (C-terminal Src kinase).
FB Description
C-terminal Src kinase (Csk) encodes a cytoplasmic tyrosine kinase that acts as a tumor suppressor through Src pathway inibition as well as a mediator of the activity of the product of Egfr.