Gene

Csk

Species
Drosophila melanogaster
Symbol
Csk
Name
C-terminal Src kinase
Synonyms
  • C-Src kinase
  • C-terminal-Src kinase
Biotype
protein coding gene
Automated Description
Enables non-membrane spanning protein tyrosine kinase activity. Involved in several processes, including adherens junction maintenance; negative regulation of imaginal disc growth; and positive regulation of hippo signaling. Predicted to be located in cell-cell junction. Predicted to be active in plasma membrane. Is expressed in salivary gland. Orthologous to several human genes including CSK (C-terminal Src kinase).
FB Description
C-terminal Src kinase (Csk) encodes a cytoplasmic tyrosine kinase that acts as a tumor suppressor through Src pathway inibition as well as a mediator of the activity of the product of Egfr.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24418
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
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11.634M11.636M11.638M11.640M11.642M11.644M11.646M11.648M11.650M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions