Predicted to enable SNARE binding activity and zinc ion binding activity. Involved in several processes, including protein localization to cell surface; regulation of tube diameter, open tracheal system; and secretion by cell. Acts upstream of with a positive effect on chitin-based cuticle development and lumen formation, open tracheal system. Located in endoplasmic reticulum exit site. Part of COPII vesicle coat. Is expressed in several structures, including adult head; circulatory system primordium; embryonic/larval midgut primordium; epithelium; and somatic trunk mesoderm derivative. Human ortholog(s) of this gene implicated in Cole-Carpenter syndrome. Orthologous to several human genes including SEC24D (SEC24 homolog D, COPII coat complex component).
FB Description
Secretory 24CD (Sec24CD) encodes a subunit of the coat protein complex of COPII vesicles, which transport cargo from the endoplasmic reticulum to the Golgi apparatus. It is essential for export of membrane and secreted proteins from the endoplasmic reticulum. It is involved in epithelial morphogenesis and differentiation.