Gene

Sec24CD

Species
Drosophila melanogaster
Symbol
Sec24CD
Name
Secretory 24CD
Synonyms
  • BcDNA:LP05220
  • CG10882
Biotype
protein coding gene
Automated Description
Predicted to enable SNARE binding activity and zinc ion binding activity. Involved in several processes, including protein localization to cell surface; regulation of tube diameter, open tracheal system; and secretion by cell. Acts upstream of with a positive effect on chitin-based cuticle development and lumen formation, open tracheal system. Located in endoplasmic reticulum exit site. Part of COPII vesicle coat. Is expressed in several structures, including adult head; circulatory system primordium; embryonic/larval midgut primordium; epithelium; and somatic trunk mesoderm derivative. Human ortholog(s) of this gene implicated in Cole-Carpenter syndrome. Orthologous to several human genes including SEC24D (SEC24 homolog D, COPII coat complex component).
FB Description
Secretory 24CD (Sec24CD) encodes a subunit of the coat protein complex of COPII vesicles, which transport cargo from the endoplasmic reticulum to the Golgi apparatus. It is essential for export of membrane and secreted proteins from the endoplasmic reticulum. It is involved in epithelial morphogenesis and differentiation.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13803
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
2.232M2.233M2.234M2.235M2.236M

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions