Gene

Rbp

Species
Drosophila melanogaster
Symbol
Rbp
Name
RIM-binding protein
Synonyms
  • CG14867
  • CG31302
Biotype
protein coding gene
Automated Description
Involved in cytoskeletal matrix organization at active zone; neuromuscular synaptic transmission; and presynaptic active zone organization. Located in cytoskeleton of presynaptic active zone. Is active in neuromuscular junction and presynaptic active zone cytoplasmic component. Is expressed in adult head and embryonic/larval neuromuscular junction. Human ortholog(s) of this gene implicated in dystonia 22, adult-onset and dystonia 22, juvenile-onset. Orthologous to several human genes including RIMBP2 (RIMS binding protein 2).
FB Description
RIM-binding protein (Rbp) encodes an active zone protein involved in neuromuscular synaptic transmission and presynaptic active zone organization.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR14234
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
15.375M15.380M15.385M15.390M15.395M15.400M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions