Version: 8.0.0
Date: Tue Jan 28 2025
Fs(2)Ket
Drosophila melanogasterFB:FBgn0262743
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Fs(2)Ket

Species
Drosophila melanogaster
Symbol
Fs(2)Ket
Name
Female sterile (2) Ketel
Synonyms
  • 38E.11
  • CG2637
Biotype
protein coding gene
Automated Description
Predicted to enable nuclear import signal receptor activity and nuclear localization sequence binding activity. Involved in NLS-bearing protein import into nucleus and regulation of nucleocytoplasmic transport. Located in P granule and nuclear envelope. Is expressed in several structures, including adult brain cell body rind; adult head; female germline cell; gonad; and lamina anlage. Orthologous to human KPNB1 (karyopherin subunit beta 1).
FB Description
Female sterile (2) Ketel (Fs(2)Ket) encodes a protein that functions in nuclear protein import, formation of the spindle apparatus and nuclear envelope assembly. It is also involved in biogenesis of the mitochondria.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10527
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
Phenotype Term
Annotation details
References
No records match query. Try removing filters.
Showing 0 - 0 of 0 rows
per page

    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
    No records match query. Try removing filters.
    Showing 0 - 0 of 0 rows
    per page
      Download all Alleles/Variants for all genes of the species

      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
      Has Disease Annotations
      Has Phenotype Annotations
      No records match query. Try removing filters.
      Showing 0 - 0 of 0 rows
      per page

        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
        Modifier
        Source
        No records match query. Try removing filters.
        Showing 0 - 0 of 0 rows
        per page

          Sequence Feature Viewer

          Genome location
          Assembly version
          R6
          Viewer Help
          Data currently unavailable; sequence viewer under construction

          Sequence Details

          Loading...

          Expression

          Primary Sources
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          Fs(2)Ket molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
          Reference
          No records match query. Try removing filters.
          Showing 0 - 0 of 0 rows
          per page

            Genetic Interactions

            Fs(2)Ket role
            Fs(2)Ket genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
            Reference
            No records match query. Try removing filters.
            Showing 0 - 0 of 0 rows
            per page