Rabaptin-5-associated exchange factor for Rab5 ortholog
Biotype
protein coding gene
Automated Description
Enables guanyl-nucleotide exchange factor activity and ubiquitin protein ligase activity. Involved in several processes, including imaginal disc-derived wing vein specification; positive regulation of protein ubiquitination; and regulation of Rab protein signal transduction. Located in apical part of cell and endocytic vesicle. Is expressed in organism and spermatozoon. Orthologous to human RABGEF1 (RAB guanine nucleotide exchange factor 1).