Gene

Atg6

Species
Drosophila melanogaster
Symbol
Atg6
Name
Autophagy-related 6
Synonyms
  • ATG6
  • atg6
Biotype
protein coding gene
Automated Description
Enables small GTPase binding activity. Involved in several processes, including glycophagy; larval midgut cell programmed cell death; and neuron remodeling. Part of phosphatidylinositol 3-kinase complex, class III, type I. Human ortholog(s) of this gene implicated in Machado-Joseph disease and breast cancer. Orthologous to several human genes including BECN1 (beclin 1).
FB Description
Autophagy-related 6 (Atg6) encodes a component of the Vps34 complex that is required for the formation of PI3P, and functions in vesicle trafficking including autophagy and endocytosis.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12768
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
24.0492M24.0494M24.0496M24.0498M24.0500M24.0502M24.0504M24.0506M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions