Gene

SNF4Aγ

Species
Drosophila melanogaster
Symbol
SNF4Aγ
Name
SNF4/AMP-activated protein kinase gamma subunit
Synonyms
  • 0050/42
  • 0127/19
Biotype
protein coding gene
Automated Description
Predicted to enable AMP binding activity; protein kinase binding activity; and protein kinase regulator activity. Involved in several processes, including behavioral response to starvation; cholesterol homeostasis; and sequestering of triglyceride. Located in cytoplasm and nucleus. Is expressed in several structures, including adult head; adult ventral nerve cord; anterior endoderm; embryonic/larval midgut primordium; and larval midline neurons. Used to study neurodegenerative disease. Human ortholog(s) of this gene implicated in Wolff-Parkinson-White syndrome; glycogen storage disease; hypertrophic cardiomyopathy 6; and lethal congenital glycogen storage disease of heart. Orthologous to several human genes including PRKAG2 (protein kinase AMP-activated non-catalytic subunit gamma 2).
FB Description
SNF4/AMP-activated protein kinase gamma subunit (SNF4Agamma) encodes a protein involved in lipid metabolism, autophagy and response to starvation.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13780
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

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Phenotypes

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    Disease Associations

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      Alleles and Variants

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        Transgenic Alleles

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        (carrying the transgene)
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          Models

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            Sequence Feature Viewer

            Genome location
            Assembly version
            R6
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            21.15M21.16M21.17M21.18M21.19M21.20M21.21M

            Sequence Details

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            Expression

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            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            SNF4Aγ molecule type
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              Genetic Interactions

              SNF4Aγ role
              SNF4Aγ genetic perturbation
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