Enables DNA-binding transcription activator activity, RNA polymerase II-specific; protein homodimerization activity; and sequence-specific DNA binding activity. Involved in several processes, including cellular response to heat; regulation of biosynthetic process; and stress-activated MAPK cascade. Located in chromocenter; nucleus; and pericentric heterochromatin. Is expressed in organism. Orthologous to several human genes including ATF2 (activating transcription factor 2).
FB Description
Activating transcription factor-2 (Atf-2) encodes a trancription factor required for heterochromatin assembly. It is involved in stress response and fat metabolism regulation.