Gene

Atf-2

Species
Drosophila melanogaster
Symbol
Atf-2
Name
Activating transcription factor-2
Synonyms
  • ATF-2
  • atf-2
Biotype
protein coding gene
Automated Description
Enables DNA-binding transcription activator activity, RNA polymerase II-specific; protein homodimerization activity; and sequence-specific DNA binding activity. Involved in several processes, including cellular response to heat; regulation of biosynthetic process; and stress-activated MAPK cascade. Located in chromocenter; nucleus; and pericentric heterochromatin. Is expressed in organism. Orthologous to several human genes including ATF2 (activating transcription factor 2).
FB Description
Activating transcription factor-2 (Atf-2) encodes a trancription factor required for heterochromatin assembly. It is involved in stress response and fat metabolism regulation.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR19304
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
24.8702M24.8704M24.8706M24.8708M24.8710M24.8712M24.8714M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions