Species

Drosophila melanogaster

Symbol

InR

Name

Insulin-like receptor

Synonyms

18402
CG18402

Biotype

protein coding gene

Automated Description

Enables insulin binding activity and insulin receptor activity. Involved in several processes, including germ cell development; negative regulation of behavior; and positive regulation of cell development. Located in plasma membrane. Part of insulin receptor complex. Is expressed in several structures, including adult fat body; corpus allatum; ganglia; gut section; and somatic precursor cell. Used to study several diseases, including alcohol dependence; diabetic neuropathy; glucose metabolism disease (multiple); high grade glioma; and sleep disorder. Human ortholog(s) of this gene implicated in several diseases, including dementia (multiple); glucose metabolism disease (multiple); kidney cancer (multiple); liver disease (multiple); and reproductive organ cancer (multiple). Orthologous to several human genes including IGF1R (insulin like growth factor 1 receptor) and INSRR (insulin receptor related receptor).

FB Description

Not Available

Cross References

Additional Information

Literature

Orthology

Gene tree: PANTHER:PTHR24416

No data available

Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources

FB

Other Sources

BioGRID CRISPR Screen Cell Line Phenotypes

Disease Associations

Cell color indicative of annotation volume

Gene	Association	Disease Qualifier	Disease	Evidence	Source	Based On	References
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Alleles and Variants

Download all Alleles/Variants for all genes of the species

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location

Chr3R:21570248...21619321 - (49.07 kb)

Assembly version

R6

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Sequence Details

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Expression