Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including nervous system development; open tracheal system development; and regulation of nucleobase-containing compound metabolic process. Located in nucleus. Is expressed in several structures, including embryonic imaginal tissue; epithelium; gut section; larval imaginal tissue; and somatic precursor cell.
FB Description
escargot (esg) encodes a Snail-type transcription factor that contributes to stem cell maintenance, tracheal morphogenesis and neuroblast differentiation.