Predicted to enable Hsp90 protein binding activity. Involved in several processes, including cellular response to heat; chaperone-mediated protein folding; and myosin filament assembly. Predicted to be active in cytoplasm. Is expressed in several structures, including adult head; dorsal pharyngeal muscle primordium; dorsal vessel; muscle cell; and somatic muscle primordium.
FB Description
uncoordinated 45 (unc-45) encodes a protein that binds the product of Hsp83 and myosin, and may may serve as a scaffold for their interaction. It is required for normal myosin accumulation and appears to play a role in myosin folding and/or protection from stress.