Enables protein homodimerization activity. Involved in several processes, including autophagic cell death; cellular response to amino acid starvation; and positive regulation of cellular component organization. Located in autophagosome membrane; cytosol; and midbody. Part of protein-containing complex.
RGD Description
This gene encodes a SRC homology 3 domain-containing protein. The encoded protein interacts with the proapoptotic member of the Bcl-2 family, Bcl-2-associated X protein (Bax) and may be involved in regulating apoptotic signaling pathways. This protein may also be involved in maintaining mitochondrial morphology. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]