Enables alpha-glucoside transmembrane transporter activity; carbohydrate:monoatomic cation symporter activity; and water transmembrane transporter activity. Involved in several processes, including alpha-glucoside transport; import across plasma membrane; and transepithelial water transport. Located in apical plasma membrane; early endosome; and perinuclear region of cytoplasm. Implicated in glucose-galactose malabsorption.
RGD Description
This gene encodes a member of the sodium-dependent glucose transporter (SGLT) family. The encoded integral membrane protein is the primary mediator of dietary glucose and galactose uptake from the intestinal lumen. Mutations in this gene have been associated with glucose-galactose malabsorption. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]