small nuclear RNA activating complex polypeptide 4
Synonyms
FLJ13451
NEDRSO
Biotype
protein coding gene
Automated Description
Enables DNA binding activity; RNA polymerase II general transcription initiation factor activity; and RNA polymerase III general transcription initiation factor activity. Involved in snRNA transcription by RNA polymerase II and snRNA transcription by RNA polymerase III. Part of snRNA-activating protein complex.
RGD Description
This gene encodes the largest subunit of the small nuclear RNA-activating protein (SNAP) complex. The encoded protein contains a Myb DNA-binding domain, and is essential for RNA polymerase II and III polymerase transcription from small nuclear RNA promoters. A mutation in this gene is associated with ankylosing spondylitis. [provided by RefSeq, Jul 2016]