Gene

SULT1E1

Species
Homo sapiens
Symbol
SULT1E1
Name
sulfotransferase family 1E member 1
Synonyms
  • EST
  • EST-1
Biotype
protein coding gene
Automated Description
Enables flavonol 3-sulfotransferase activity and steroid sulfotransferase activity. Involved in several processes, including 3'-phosphoadenosine 5'-phosphosulfate metabolic process; estrogen catabolic process; and ethanol catabolic process. Acts upstream of or within sulfation. Located in cytosol and nuclear membrane. Implicated in breast cancer and endometrial cancer.
RGD Description
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that transfers a sulfo moiety to and from estrone, which may control levels of estrogen receptors. [provided by RefSeq, Jul 2008]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11783
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
69.825M69.830M69.835M69.840M69.845M69.850M69.855M69.860M

Sequence Details

Loading...

Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions