mediator of RNA polymerase II transcription subunit 21
Biotype
protein coding gene
Automated Description
Enables transcription coactivator activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Part of core mediator complex and mediator complex.
RGD Description
This gene encodes a member of the mediator complex subunit 21 family. The encoded protein interacts with the human RNA polymerase II holoenzyme and is involved in transcriptional regulation of RNA polymerase II transcribed genes. A pseudogene of this gene is located on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]