Gene

MED21

Species
Homo sapiens
Symbol
MED21
Name
mediator complex subunit 21
Synonyms
  • hSrb7
  • mediator of RNA polymerase II transcription subunit 21
Biotype
protein coding gene
Automated Description
Enables transcription coactivator activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Part of core mediator complex and mediator complex.
RGD Description
This gene encodes a member of the mediator complex subunit 21 family. The encoded protein interacts with the human RNA polymerase II holoenzyme and is involved in transcriptional regulation of RNA polymerase II transcribed genes. A pseudogene of this gene is located on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13381
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
27.025M27.030M27.035M27.040M27.045M27.050M27.055M27.060M27.065M

Sequence Details

Loading...

Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions