Version: 8.0.0Date: Tue Jan 28 2025
Gene
TARS1
- Species
- Homo sapiens
- Symbol
- TARS1
- Name
- threonyl-tRNA synthetase 1
- Synonyms
- MGC9344
- TARS
- Biotype
- protein coding gene
- Automated Description
- Enables several functions, including ATP binding activity; threonine-tRNA ligase activity; and zinc ion binding activity. Involved in threonyl-tRNA aminoacylation. Located in extracellular exosome. Implicated in nonphotosensitive trichothiodystrophy 7.
- RGD Description
- Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Threonyl-tRNA synthetase belongs to the class-II aminoacyl-tRNA synthetase family [provided by RefSeq, Jul 2008]
- Cross References
- Additional Information
- Literature
Orthology
- Gene tree
- PANTHER:PTHR11451
Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse
Disease Associations
Cases where the expected disease association was NOT found
Cell color indicative of annotation volume
Gene | Association | Disease Qualifier | Disease | Evidence | Source | Based On | References |
|---|---|---|---|---|---|---|---|
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Sequence Feature Viewer
- Genome location
- Chr5:33440696...33468091 + (27.40 kb)
- Assembly version
- GRCh38
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