Gene

TRHR

Species
Homo sapiens
Symbol
TRHR
Name
thyrotropin releasing hormone receptor
Synonyms
  • CHNG7
  • MGC141920
Biotype
protein coding gene
Automated Description
Predicted to enable thyrotropin-releasing hormone receptor activity. Predicted to be involved in phospholipase C-activating G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Implicated in congenital nongoitrous hypothyroidism 7 and hypertension.
RGD Description
This gene encodes a G protein-coupled receptor for thyrotropin-releasing hormone (TRH). Upon binding to TRH, this receptor activates the inositol phospholipid-calcium-protein kinase C transduction pathway. Mutations in this gene have been associated with generalized thyrotropin-releasing hormone resistance. [provided by RefSeq, Sep 2011]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR46061
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
109.090M109.095M109.100M109.105M109.110M109.115M109.120M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions