Gene

POLR3K

Species
Homo sapiens
Symbol
POLR3K
Name
RNA polymerase III subunit K
Synonyms
  • C11
  • C11-RNP3
Biotype
protein coding gene
Automated Description
Enables zinc ion binding activity. Predicted to be involved in termination of RNA polymerase III transcription. Part of RNA polymerase III complex. Implicated in hypomyelinating leukodystrophy 21.
RGD Description
This gene encodes a small essential subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The carboxy-terminal domain of this subunit shares a high degree of sequence similarity to the carboxy-terminal domain of an RNA polymerase II elongation factor. This similarity in sequence is supported by functional studies showing that this subunit is required for proper pausing and termination during transcription. Pseudogenes of this gene are found on chromosomes 13 and 17.[provided by RefSeq, Jul 2010]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11239
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
47k48k49k50k51k52k53k

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions