Predicted to enable calcium ion binding activity. Involved in photoreceptor cell maintenance; photoreceptor cell morphogenesis; and photoreceptor cell outer segment organization. Predicted to be located in photoreceptor outer segment membrane. Predicted to be active in plasma membrane. Implicated in cone-rod dystrophy 15.
RGD Description
This gene belongs to the cadherin superfamily of calcium-dependent cell adhesion molecules. The encoded protein is a photoreceptor-specific cadherin that plays a role in outer segment disc morphogenesis. Mutations in this gene are associated with inherited retinal dystrophies. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2013]