Gene

FARSB

Species
Homo sapiens
Symbol
FARSB
Name
phenylalanyl-tRNA synthetase subunit beta
Synonyms
  • FARSLB
  • FRSB
Biotype
protein coding gene
Automated Description
Enables phenylalanine-tRNA ligase activity. Involved in phenylalanyl-tRNA aminoacylation and protein heterotetramerization. Located in membrane. Part of phenylalanine-tRNA ligase complex.
RGD Description
This gene encodes a highly conserved enzyme that belongs to the aminoacyl-tRNA synthetase class IIc subfamily. This enzyme comprises the regulatory beta subunits that form a tetramer with two catalytic alpha subunits. In the presence of ATP, this tetramer is responsible for attaching L-phenylalanine to the terminal adenosine of the appropriate tRNA. A pseudogene located on chromosome 10 has been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10947
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
222.57M222.58M222.59M222.60M222.61M222.62M222.63M222.64M222.65M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions