Gene

AMOTL2

Species
Homo sapiens
Symbol
AMOTL2
Name
angiomotin like 2
Synonyms
  • angiomotin-like protein 2
  • LCCP
Biotype
protein coding gene
Automated Description
Predicted to enable actin filament binding activity and identical protein binding activity. Involved in positive regulation of protein localization. Located in cytoplasm and podosome.
RGD Description
Angiomotin is a protein that binds angiostatin, a circulating inhibitor of the formation of new blood vessels (angiogenesis). Angiomotin mediates angiostatin inhibition of endothelial cell migration and tube formation in vitro. The protein encoded by this gene is related to angiomotin and is a member of the motin protein family. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR14826
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
134.356M134.358M134.360M134.362M134.364M134.366M134.368M134.370M134.372M134.374M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions