Gene

COMMD5

Species
Homo sapiens
Symbol
COMMD5
Name
COMM domain containing 5
Synonyms
  • COMM domain-containing protein 5
  • FLJ13008
Biotype
protein coding gene
Automated Description
Predicted to be involved in proximal tubule morphogenesis. Located in cytosol and nucleoplasm.
RGD Description
Predicted to be involved in proximal tubule morphogenesis. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Nov 2024]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR15666
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Mus musculusCommd510 of 10YesYes  
Rattus norvegicusCommd510 of 10YesYes  
Xenopus laeviscommd5.L1 of 1YesYes           
Xenopus tropicaliscommd59 of 9YesYes   
Danio reriocommd59 of 10YesYes  
Drosophila melanogasterLSm-45 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

No paralogs for the gene.

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

Genome location
Assembly version
GRCh38
Viewer Help
144.838M144.840M144.842M144.844M144.846M144.848M144.850M144.852M
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
NC_000008.11:g.144842315A>Gvariant
SNP
  • intron variant
NC_000008.11:g.144842386C>Tvariant
SNP
  • intron variant
NC_000008.11:g.144841657C>Gvariant
SNP
  • intron variant
NC_000008.11:g.144841715A>Gvariant
SNP
  • intron variant
NC_000008.11:g.144842144A>Cvariant
SNP
  • intron variant
NC_000008.11:g.144850885C>Avariant
SNP
  • missense variant
NC_000008.11:g.144841988T>Cvariant
SNP
  • intron variant
NC_000008.11:g.144841361C>Tvariant
SNP
  • intron variant
NC_000008.11:g.144850680C>Tvariant
SNP
  • missense variant
NC_000008.11:g.144842425C>Gvariant
SNP
  • intron variant
Showing 1 - 10 of 41 rows
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Transgenic Alleles

Species
(carrying the transgene)
Allele symbol
Transgenic construct
Expressed components
Knock-down targets
Regulatory regions
Has Disease Annotations
Has Phenotype Annotations
Drosophila melanogasterHsap\COMMD5UAS.Tag:HA
  • UASt
Showing 1 - 1 of 1 rows
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Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
144.838M144.840M144.842M144.844M144.846M144.848M144.850M144.852M

Sequence Details

Transcript: Mode:

Expression

Primary Sources
None
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

58 interactor genes based on 85 annotations
COMMD5 molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
ACSF2Homo sapiens
protein
  • affinity chromatography technology
PMID:33961781
protein
BBS2Homo sapiens
protein
  • affinity chromatography technology
PMID:33961781
protein
BLTP2Homo sapiens
protein
  • affinity chromatography technology
PMID:33961781
protein
CCDC22Homo sapiens
protein
  • affinity chromatography technology
PMID:26496610
protein
CCDC22Homo sapiens
protein
  • affinity chromatography technology
PMID:28514442
protein
CCDC22Homo sapiens
protein
  • affinity chromatography technology
PMID:33961781
protein
CCDC22Homo sapiens
protein
  • affinity chromatography technology
PMID:35271311
protein
CCDC93Homo sapiens
protein
  • affinity chromatography technology
PMID:33961781
protein
CCDC93Homo sapiens
protein
  • affinity chromatography technology
PMID:26496610
protein
CCDC93Homo sapiens
protein
  • affinity chromatography technology
PMID:35271311
Showing 1 - 10 of 84 rows
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Genetic Interactions

COMMD5 role
COMMD5 genetic perturbation
Interactor gene
Interactor species
Interactor role
Interactor genetic perturbation
Interaction type
Phenotype or trait
Source
Reference
unspecified role
RB1Homo sapiens
unspecified role
negative genetic interaction (sensu BioGRID)
  • Growth abnormality, viability
PMID:35559673
Showing 1 - 1 of 1 rows
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