Gene

VEZT

Species
Homo sapiens
Symbol
VEZT
Name
vezatin, adherens junctions transmembrane protein
Synonyms
  • DKFZp761C241
  • transmembrane protein vezatin
Biotype
protein coding gene
Automated Description
Predicted to enable myosin binding activity. Predicted to be involved in cell-cell adhesion and synapse maturation. Predicted to act upstream of or within chordate embryonic development. Located in cytosol and nucleoplasm.
RGD Description
This gene encodes a transmembrane protein which has been localized to adherens junctions and shown to bind to myosin VIIA. Examination of expression of this gene in gastric cancer tissues have shown that expression is decreased which appears to be related to hypermethylation of the promoter. Expression of this gene may also be inhibited by binding of a specific microRNA to a target sequence in the 3' UTR of the transcripts. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR15989
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
95.22M95.23M95.24M95.25M95.26M95.27M95.28M95.29M95.30M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions