Gene

HIPK4

Species
Homo sapiens
Symbol
HIPK4
Name
homeodomain interacting protein kinase 4
Synonyms
  • FLJ32818
  • homeodomain-interacting protein kinase 4
Biotype
protein coding gene
Automated Description
Predicted to enable protein serine/threonine kinase activity and protein tyrosine kinase activity. Predicted to be involved in chromatin remodeling. Predicted to act upstream of or within peptidyl-serine phosphorylation; protein autophosphorylation; and regulation of signal transduction by p53 class mediator. Predicted to be active in cytoplasm and nucleus.
RGD Description
This gene encodes a member of the homeodomain interacting protein kinase (HIPK) family of proteins. While other members of this family are found throughout vertebrates, this member is present only in mammals. Compared to other members of this family, the encoded protein lacks a nuclear localization signal and a C-terminal autoinhibitory domain. The encoded protein exhibits kinase activity and may phosphorylate the tumor suppressor protein p53. [provided by RefSeq, Jul 2016]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24058
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
40.380M40.381M40.382M40.383M40.384M40.385M40.386M40.387M40.388M40.389M40.390M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions